Services de recherche
Notre Bureau de la recherche facilite les activités de recherche au sein de Santé Ontario afin de soutenir notre communauté de recherche, nos scientifiques et nos programmes, notamment en :
- proposant des services pour vous accompagner dans le processus de recherche (aspects juridiques, financiers, protection de la vie privée, publication, lettres de soutien et accès à nos données)
- renforçant les relations avec les partenaires en vue de collaborations de recherche et de demandes de subventions
- jetant les bases de la recherche en proposant des activités de transfert et d'échange de connaissances
Études auprès des patients
Nous gérons le processus de recrutement et de consentement des scientifiques qui souhaitent obtenir la participation de personnes en Ontario à des recherches en santé publique. Le processus de l’étude sur les contacts avec les patients est approuvé par le Commissaire à l'information et à la protection de la vie privée de l’Ontario (CIPVP) et comprend de nombreuses garanties juridiques et de protection de la vie privée concernant les précieuses données de santé recueillies par Santé Ontario. Le Bureau de la recherche contacte par courrier les participants potentiels dans toute la province pour les inviter à participer à une étude de recherche. Si la personne y consent, le chercheur prend ensuite contact avec elle pour mener à bien son étude. Grâce au processus d'étude de contact avec les patients approuvé par le CIPVP, nous veillons à ce que les personnes soient en mesure de prendre des décisions éclairées lorsqu'elles consentent et participent à la recherche.
Mesure et surveillance
Nos scientifiques et les membres de notre équipe de recherche dirigent et participent également à plusieurs activités de recherche sur la performance des systèmes, notamment l’ International Cancer Benchmarking Partnership (ICBP) et le programme CONCORD.
Recherche publiée
Les recherches menées par les scientifiques, les responsables des soins cliniques et le personnel travaillant pour Santé Ontario sont publiées dans des revues et des rapports scientifiques de premier plan, évalués par des pairs.
Pour obtenir une liste de recherches menées par Santé Ontario, y compris des articles sur le cancer, les maladies rénales, les affections cardiaques et d'autres sujets liés à la santé, consultez PubMed.
Les publications référencées ci-dessous sont disponibles en anglais seulement.
DeBono NL, Everest L, Berriault C, Nguyen L, Arrandale VH, Demers PA, Kirkham TL. Quantitative silica dust exposure and lung cancer incidence in hard rock miners: 1.6 million person-years of follow-up in the Mining Master File cohort study. Occup Environ Med. 2026 Jul 22;83(4):188-194. doi: 10.1136/oemed-2026-110906. PMID: 42270323.
Dubé C, Kyei A, Hatvani A, Walker M, Gao J, Ahn J, Morgan D, Baxter NN, Rabeneck L, Tinmouth J. Taking a pragmatic approach to implement colonoscopy quality at a health system level: Ontario’s colonoscopy quality strategy. J Can Assoc Gastroenterol. 2026 Jul 30:gwag028.
Fleming R, Crivellaro PS, Fienberg S, Koberstein W, Kornecki A, Mnyusiwalla A, Zahra S, Flegg C. CAR Practice Guidelines on Breast Imaging and Interventions: Mammography and Digital Breast Tomosynthesis. Can Assoc Radiol J. 2026 May 26:8465371261451252. doi: 10.1177/08465371261451252. Epub ahead of print. PMID: 42198822.
Gillan C, Liszewski B, Hsu A, Rahman F, Ebady M, Nielsen M, Aloysious C, Lai Y, Brown E, Donaldson H, Caissie A. The complementary roles of oversight, education, and collaboration in the responsible integration of artificial intelligence in radiation medicine: White paper of (CADRA). J Med Imaging Radiat Sci. 2026 Sep;57(5):102436. doi: 10.1016/j.jmir.2026.102436. Epub 2026 Jun 25. PMID: 42349037.
Llovet D, Patel J, Gotlib Conn L, Sargeant J, Baxter NN, Ivers N, Morgan D, Paszat L, Rabeneck L, Tinmouth J. Multicomponent audit and feedback for colonoscopy quality improvement among potentially lower-performing endoscopists. J Can Assoc Gastroenterol. 2026 Mar 27;9(4):190-203. doi: 10.1093/jcag/gwag010. PMID: 42553765; PMCID: PMC13436815.
Metser U, Bauman G, Rashid M, Mirshahvalad SA, Kohan A, Green B, Chan R, Hamilton R. Utility of PSMA PET/CT After an Initial Negative Scan: Results from a Prospective Multicenter PSMA PET Registry. J Nucl Med. 2026 Jul 1;67(7):1097-1101. doi: 10.2967/jnumed.126.272204. PMID: 41991335.
Morgan E, Bardot A, Langselius O, Rutherford MJ, Elkader HA, Bennett D, Brennan A, Bucher O, Butler J, Cameron DA, Canfell K, Chiam K, Chiarelli A, Creighton N, De P, Evans S, Fitzpatrick D, Guren MG, Hannah J, Huws DW, Jackson CGCA, Kønig SM, Kumar E, Larønningen S, Lawler M, Liu Q, McClure C, Mehmood A, Mitchell H, Morrison DS, Murray D, Norwood T, Phillips KAM, Ransom D, Shack L, Smits S, Saint-Jacques N, Marvelde LT, Tran D, Turner D, Ursin G, Vernon S, Walker MJ, Woods RR, Zhang B, Bray F, Soerjomataram I. International disruptions to cancer diagnosis and stage at presentation during the COVID-19 pandemic in 2020: an International Cancer Benchmarking Partnership (ICBP) population-based study. Lancet Oncol. 2026 Jun;27(6):738-750. doi: 10.1016/S1470-2045(26)00089-6. PMID: 42225103; PMCID: PMC13226152.
Mozessohn L, Villeneuve PJA, Somé NH, Mercer RE, Masucci L, Kouroukis T, Bredeson C, Aktar S, Guan Q, Prica A, Chen CI, Rodin D, Cheung MC, Chaudhry M, Gavura S, McKay C, Wong WWL, Chan KKW. A Prospective Population-Based Study of Chimeric Antigen Receptor T-Cell Therapy for Patients with Diffuse Large B-Cell Lymphoma. Curr Oncol. 2026 Jun 18;33(6):366. doi: 10.3390/curroncol33060366. PMID: 42346266; PMCID: PMC13297695.
Muñoz C, Arias J, Brown A, Garg M, Gavura S. Coverage With Evidence Development: An Environmental Scan of Funding Programs Leveraging Real-World Evidence to Support Funding Decisions. Can J Health Technol. 2026 Apr 2;6(4). doi: 10.51731/cjht.2026.1406.
O'Sullivan DE, Eros FR, DeBono NL, Demers PA, Peters CE, Sritharan J. Ultraviolet radiation exposure and melanoma risk among over 2 million Ontario workers. Sci Rep. 2026 Apr 10;16(1):16793. doi: 10.1038/s41598-026-48477-4. PMID: 41963456; PMCID: PMC13223300.
Rabeneck L, Tinmouth J, Hutchinson JM, Ruan Y, Hilsden RJ, Warkentin MT, Telford JJ, Singh H, Dobrow MJ, Barkun AN, Llovet D, McGrath J, Sheppard AJ, Dubé C, du Plessis H, Wong CKW, Cleary SP, Coldman AJ, Heitman SJ, Senese LC, Brenner DR; Canadian Colorectal Cancer Screening Research Network. Should we screen for colorectal cancer with biennial FIT beginning at age 45 in Canada? J Can Assoc Gastroenterol. 2026 Mar 7;9(2):61-71. doi: 10.1093/jcag/gwag008. PMID: 42058692; PMCID: PMC13123671.
Safieh-Garabedian N, Antoniou AC, Brooks J, Carroll J, Cavaillé M, Chiquette J, DeCoteau MJ, Doyle G, Eisen A, Eloy L, Feinberg S, Freitas V, Hender K, Kulkarni S, Mbuya-Bienge C, Molnar C, Nabi H, Samson C, Seely JM, Sheppard AJ, Soucy P, Tagyen R, Trop I, Turgeon A, Venturi M, Wadden N, Walker M, Wolfson M, Chiarelli A, Simard J, Pashayan N. Perspectives from a multi-stakeholder workshop for implementing a risk-stratified breast cancer screening program in Canada. Commun Med (Lond). 2026 Apr 21;6(1):242. doi: 10.1038/s43856-026-01582-x. PMID: 42014777; PMCID: PMC13109382.
Saini G, Lowe M, Ellison LK, Elias B, Tjepkema M, Letendre A, Kewayosh A, Marrett LD, Sheppard AJ. Investigating kidney cancer outcomes among First Nations adults in Canada, 2006− 2015: Followup of the 2006 Canadian Census Health and Environmental Cohort (CanCHEC). Can Urol Assoc J. 2026 Jul 7;20(10). doi: 10.5489/cuaj.9617.
Sheppard AJ, Sutradhar R, Liu N, Kewayosh A, Leylachian S, Senese L, Ianni A, Hyett S, Chiarelli AM, Kupets R, Tammemägi CM, Tinmouth J. Population-Level Outcomes for Screening Program Cancers in First Nations People in Ontario, Canada. JAMA Netw Open. 2026 Jul 1;9(7):e2622718. doi: 10.1001/jamanetworkopen.2026.22718. PMID: 42430169; PMCID: PMC13355153.
Thompson T, Goggins K, Demers PA, Jardine KJ, Parker M, Sritharan J. Occupational disease risks in natural resource-based industries among a large cohort of workers in Ontario, Canada. Work. 2026 Aug 21:10519815261476663. doi: 10.1177/10519815261476663. Epub ahead of print. PMID: 42627631.
Villeneuve PJA, Mozessohn L, Somé NH, Mercer RE, Masucci L, , Kouroukis T Bredeson C, Aktar S, Guan Q, Prica A, Chen CI, Rodin D, Cheung M, Chaudhry M, Gavura S, McKay C, Wong WWL, Chan KKW. Comparative effectiveness of chimeric antigen receptor (CAR) T-cell therapy versus historical controls in patients with relapse/refractory aggressive B-cell lymphoma: An indirect treatment comparison in the real-world setting. Br J Haematol. 2026 Jul 6. doi: 10.1111/bjh.70632. Epub ahead of print. PMID: 42410301.
Yang X, Usher-Smith JA, Blackmore KM, Brooks JD, Bell KA, Carver T, Chang A, Chiquette J, Easton DF, Eisen A, Eloy L, Fienberg S, Joly Y, Kim RH, Knoppers BM, Lambert-Côté L, Nabi H, Pashayan N, Soucy P, Stockley TL, Turgeon A, Walker MJ, Wolfson M, Dorval M, Chiarelli AM, Antoniou AC, Simard J. Contribution of Risk Factors, Including Polygenic Score, to the Multifactorial Risk Assessment for the Implementation of Personalized Breast Cancer Screening: Insights from the PERSPECTIVE: Integration and Implementation Project. Cancers (Basel). 2026 May 5;18(9):1482. doi: 10.3390/cancers18091482. PMID: 42122278; PMCID: PMC13162589.
Ziembicki S, Kirkham TL, Arrandale VH, Navaneelan T, Demers PA. Cancer, chronic obstructive pulmonary disease and ischaemic heart disease in Ontario, Canada workers exposed to diesel engine exhaust. Occup Environ Med. 2026 May 21;83(2):78-84. doi: 10.1136/oemed-2025-110689. PMID: 42055809.
Bouchard-Fortier G, Ante Z, Liu N, Covens A, Eiriksson L, Osborne R, Pulman K, Swift BE, Gien LT. Patterns of Care of Gestational Trophoblastic Disease in Ontario: a Population-based Study. Int J Gynecol Cancer. 2026 May;36(5):104640. doi: 10.1016/j.ijgc.2026.104640. Epub 2026 Mar 11. PMID: 41936272.
Davies GA, Prica A, Ante Z, Liu N, Pond GR, Balitsky AK, Suleman A, Mozessohn L. Secondary primary malignancies in indolent non-Hodgkin lymphoma patients receiving frontline bendamustine-rituximab. Cancer. 2026 Mar 1;132(5):e70327. doi: 10.1002/cncr.70327. PMID: 41773899; PMCID: PMC12955526.
Fatiregun OA, Sutradhar R, Podolsky S, Eisen A, Paszat L, Rakovitch E. Mammographic screening and time to breast cancer diagnosis among immigrants and long-term residents in Ontario. BMC Cancer. 2026 Mar 19;26(1):535. doi: 10.1186/s12885-026-15693-0. PMID: 41851664; PMCID: PMC13126999.
Gupta G, Podolsky S, Liu N, Cheung MC, Bankar A. Frailty and health resource utilization in 5450 adults with acute myeloid leukaemia: A population-based study from Ontario, Canada. Br J Haematol. 2026 Aug;209(2):601-609. doi: 10.1111/bjh.70600. Epub 2026 Jun 8. PMID: 42259647; PMCID: PMC13461992.
Hanna NM, Shakeel S, Akhtar-Danesh GG, Finley C, Akhtar-Danesh N. A population-based study on the impact of social determinants of health on time to treatment of stage I lung cancer in Ontario, Canada. BMC Cancer. 2026 May 20;26(1):856. doi: 10.1186/s12885-026-15875-w. PMID: 42163198; PMCID: PMC13378072.
Hansford RLW, Davis LE, Griffiths R, Horrill T, Nguyen P, Goldie CL, Hanna TP, Mahar AL. Receipt of cancer care among stage IV non-small-cell lung cancer patients with and without intellectual or developmental disabilities: A population-based retrospective cohort study. Palliat Med. 2026 Jul 23:2692163261464345. doi: 10.1177/02692163261464345. Epub ahead of print. PMID: 42490651.
Khosh Kish E, Dvorani E, Saskin R, Wilton AS, Satkunasivam R, Aminoltejari K, Hird A, Berscheid K, Roy S, Morgan SC, Ong M. Forecasting Trends in Androgen Deprivation Therapy Intensification for Metastatic Hormone-Sensitive Prostate Cancer: A Retrospective Population-Based Cohort and Time-Series Analysis. Curr Oncol. 2026 May 8;33(5):276. doi: 10.3390/curroncol33050276. PMID: 42187593; PMCID: PMC13204879.
Knight KA, Brennan KE, McKechnie TJ, Kong W, Brown CJ, Heneghan CJ, Bankhead CR, Farooq AO, Patel SV. Revisiting the rationale for radical resection in low-risk early rectal cancer: a population-level perspective. Eur J Surg Oncol. 2026 Jul 21;52(10):112023. doi: 10.1016/j.ejso.2026.112023. PMID: 42556148.
Mavros MN, Ladak F, Chan KKW, Nguyen L, Coburn NG, Raphael MJ. The association between cardiovascular medication use and survival in patients with advanced pancreatic adenocarcinoma. Ther Adv Med Oncol. 2026 May 6;18:17588359261449094. doi: 10.1177/17588359261449094. PMID: 42131260; PMCID: PMC13161621.
Nakajima E, Nguyen L, Liu N, Rodin D, Amir E, Austin PC, Thavendiranathan P, Abdel-Qadir H. Long-Term Risk of Cardiovascular Disease After Contemporary Left-Sided Breast Radiation Therapy. JAMA Netw Open. 2026 Apr 1;9(4):e264098. doi: 10.1001/jamanetworkopen.2026.4098. PMID: 41920543; PMCID: PMC13044663.
Yeung KD, Pond G, Kong I, Zhang H, Gupta M, Chen Z, Lee J. Incidence and Management Trends in Advanced Head and Neck Non-Melanoma Skin Cancer in Ontario. Curr Oncol. 2026 May 17;33(5):291. doi: 10.3390/curroncol33050291. PMID: 42187608; PMCID: PMC13205009.
Zeng H, Nguyen L, He J, Liu N, Baxter NN, Coburn NG, Roberts A, Liaqat A, Zhong T. Patient-Reported Longitudinal Symptom Patterns Following Breast-Conserving Surgery versus Mastectomy with or without Immediate Breast Reconstruction: A Retrospective Cohort Study. Eur J Surg Oncol. 2026 Aug 5;52(10):112055. doi: 10.1016/j.ejso.2026.112055. PMID: 42580202.
Contactez-nous
Vous pouvez obtenir des renseignements sur la façon de soumettre une demande d’études auprès des patients ou de trouver du soutien pour votre projet de recherche en santé en communiquant avec le Bureau de la recherche de Santé Ontario grâce à notre formulaire de contact.
Dernière Mise à Jour: 26 octobre 2026
